Hydroxylamine, O-[(1,1-dimethylethyl)diphenylsilyl]-


Chemical Name: Hydroxylamine, O-[(1,1-dimethylethyl)diphenylsilyl]-
CAS Number: 103587-51-5
Product Number: AG003TF1(AGN-PC-00F4X9)
Synonyms:
MDL No: MFCD06809831
Molecular Formula: C16H21NOSi
Molecular Weight: 271.4295

Identification/Properties


Properties
MP:
82 - 85°C
Storage:
Inert atmosphere;-10 ℃;
Form:
Solid
Computed Properties
Molecular Weight:
271.435g/mol
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
2
Rotatable Bond Count:
4
Exact Mass:
271.139g/mol
Monoisotopic Mass:
271.139g/mol
Topological Polar Surface Area:
35.2A^2
Heavy Atom Count:
19
Formal Charge:
0
Complexity:
257
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information


NMR Spectrum


Other Analytical Data


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Chemical Structure



O-(tert-Butyldiphenylsilyl)hydroxylamine is a versatile reagent widely used in organic synthesis as a protecting group for amines, especially in cases where steric hindrance or sensitivity to harsh reaction conditions are concerns. This compound finds application in the protection of primary and secondary amines, allowing for selective reactions to occur at other functional groups without interference. By forming stable silyl derivatives, O-(tert-Butyldiphenylsilyl)hydroxylamine enables chemists to control the reactivity of amine-containing compounds, facilitating the synthesis of complex organic molecules with precision and efficiency. Additionally, the deprotection of the silyl group can be easily achieved under mild conditions, making this reagent a valuable tool in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals.