2,5-Pyrrolidinedione, 1-(2-hydroxyethyl)-


Chemical Name: 2,5-Pyrrolidinedione, 1-(2-hydroxyethyl)-
CAS Number: 18190-44-8
Product Number: AG00237N(AGN-PC-0JOCP2)
Synonyms:
MDL No:
Molecular Formula: C6H9NO3
Molecular Weight: 143.1406

Identification/Properties


Properties
MP:
57-61 °C(lit.)
BP:
160-164 °C3 mm Hg(lit.)
Storage:
Inert atmosphere;Room Temperature;
Form:
Solid
Refractive Index:
1.4290 (estimate)
Computed Properties
Molecular Weight:
143.142g/mol
XLogP3:
-1.5
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
3
Rotatable Bond Count:
2
Exact Mass:
143.058g/mol
Monoisotopic Mass:
143.058g/mol
Topological Polar Surface Area:
57.6A^2
Heavy Atom Count:
10
Formal Charge:
0
Complexity:
150
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information


GHS Pictogram:
Signal Word:
Warning
UN#:
N/A
Hazard Statements:
H315-H319-H335
Precautionary Statements:
P261-P305+P351+P338
Class:
N/A
Packing Group:
N/A

NMR Spectrum


Other Analytical Data


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Chemical Structure



N-(2-Hydroxyethyl)succinimide is a versatile compound commonly employed in chemical synthesis as a key intermediate in various reactions. Its hydroxyethyl functional group enhances its reactivity, making it particularly valuable in the field of organic chemistry. One of the prominent applications of N-(2-Hydroxyethyl)succinimide is in peptide coupling reactions, where it serves as an effective coupling agent for the synthesis of peptides. Additionally, this compound is commonly utilized in the modification of biomolecules and pharmaceutical compounds due to its ability to selectively react with specific functional groups. Its unique structure and properties make N-(2-Hydroxyethyl)succinimide an indispensable tool for organic chemists seeking to carry out complex synthetic transformations with precision and control.