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Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

Boronic acid, (3,5-difluorophenyl)-

OB(c1cc(F)cc(c1)F)O Request for Quotation
Chemical Name: Boronic acid, (3,5-difluorophenyl)-
CAS Number: 156545-07-2
Product Number: AG001OSE(AGN-PC-0KK6IB)
Synonyms:
MDL No: MFCD01318138
Molecular Formula: C6H5BF2O2
Molecular Weight: 157.9105

Identification/Properties

Properties
MP:
210-217 °C
BP:
266.9°C at 760 mmHg
Storage:
Keep in dry area;2-8℃;
Form:
Solid
Computed Properties
Molecular Weight:
157.911g/mol
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
4
Rotatable Bond Count:
1
Exact Mass:
158.035g/mol
Monoisotopic Mass:
158.035g/mol
Topological Polar Surface Area:
40.5A^2
Heavy Atom Count:
11
Formal Charge:
0
Complexity:
124
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

NMR Spectrum

Other Analytical Data

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Chemical Structure


The 3,5-Difluorophenylboronic acid is a versatile compound widely utilized in chemical synthesis. One of its key applications is in Suzuki-Miyaura cross-coupling reactions, where it serves as a crucial boronic acid building block. This reaction involves the coupling of an aryl or vinyl boronic acid with an organic halide or pseudohalide in the presence of a palladium catalyst to form a new carbon-carbon bond. Furthermore, 3,5-Difluorophenylboronic acid is utilized in the preparation of complex pharmaceutical compounds, agrochemicals, and materials science. Its unique fluorine substituents offer enhanced reactivity and selectivity in various transformations, making it a valuable tool for organic chemists. Additionally, this compound can be used as a precursor for the introduction of the difluorophenyl group into target molecules, providing a way to modulate their properties for specific applications.