Phosphine, dicyclohexyl(2'-methyl[1,1'-biphenyl]-2-yl)-


Chemical Name: Phosphine, dicyclohexyl(2'-methyl[1,1'-biphenyl]-2-yl)-
CAS Number: 251320-86-2
Product Number: AG002QL0(AGN-PC-0KK6TQ)
Synonyms:
MDL No:
Molecular Formula: C25H33P
Molecular Weight: 364.5033

Identification/Properties


Computed Properties
Molecular Weight:
364.513g/mol
XLogP3:
7.1
Hydrogen Bond Donor Count:
0
Hydrogen Bond Acceptor Count:
0
Rotatable Bond Count:
4
Exact Mass:
364.232g/mol
Monoisotopic Mass:
364.232g/mol
Topological Polar Surface Area:
0A^2
Heavy Atom Count:
26
Formal Charge:
0
Complexity:
388
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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Chemical Structure



2-(Dicyclohexylphosphino)-2'-methylbiphenyl, commonly known as $name$, plays a crucial role in chemical synthesis as a versatile ligand in organometallic catalysis and coordination chemistry. Due to its unique molecular structure, $name$ exhibits excellent chelating capabilities, making it an ideal candidate for facilitating a wide range of metal-catalyzed reactions in organic synthesis.In transition metal catalysis, $name$ can complex with various metals such as palladium, nickel, or rhodium to form stable coordination complexes. These complexes serve as catalysts in a plethora of reactions including cross-coupling, C-H activation, and asymmetric synthesis. The dicyclohexylphosphino group provides steric hindrance, influencing the regioselectivity and enantioselectivity of the catalytic reactions.Moreover, the methyl-substituted biphenyl moiety in $name$ imparts additional structural rigidity and electron density to the ligand-metal complex, further enhancing its catalytic activity and stability. This enables precise control over the reaction pathways and leads to improved yields and selectivities in the synthesis of complex organic molecules.In summary, the application of 2-(Dicyclohexylphosphino)-2'-methylbiphenyl in chemical synthesis lies in its ability to serve as an efficient and versatile ligand for metal-catalyzed transformations, offering chemists a powerful tool to access a diverse array of structurally complex and functionally important compounds.