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Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

Acetamide, 2,2,2-trifluoro-N-(hydroxymethyl)-

OCNC(=O)C(F)(F)F Request for Quotation
Chemical Name: Acetamide, 2,2,2-trifluoro-N-(hydroxymethyl)-
CAS Number: 50667-69-1
Product Number: AG003SEK(AGN-PC-0KP0QO)
Synonyms:
MDL No:
Molecular Formula: C3H4F3NO2
Molecular Weight: 143.0646

Identification/Properties

Properties
MP:
102-103°C
BP:
236.6°C at 760 mmHg
Storage:
Keep in dry area;2-8℃;
Form:
Solid
Computed Properties
Molecular Weight:
143.065g/mol
XLogP3:
0.1
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
5
Rotatable Bond Count:
1
Exact Mass:
143.019g/mol
Monoisotopic Mass:
143.019g/mol
Topological Polar Surface Area:
49.3A^2
Heavy Atom Count:
9
Formal Charge:
0
Complexity:
110
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

GHS Pictogram:
Signal Word:
Warning
UN#:
N/A
Hazard Statements:
H315-H319-H335
Precautionary Statements:
P233-P260-P261-P264-P271-P280-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501
Class:
N/A
Packing Group:
N/A

NMR Spectrum

Other Analytical Data

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Chemical Structure


2,2,2-Trifluoro-N-(hydroxymethyl)acetamide is a versatile compound widely used in chemical synthesis as a key building block for the construction of various pharmaceuticals, agrochemicals, and materials. This compound serves as a crucial intermediate for the synthesis of diverse chemical structures due to its unique properties and reactivity. As a fluorinated organic compound, 2,2,2-Trifluoro-N-(hydroxymethyl)acetamide exhibits enhanced stability and lipophilicity, making it a valuable tool in medicinal chemistry for the development of fluorine-containing drugs. Its hydroxymethyl functional group provides a site for further modification through various chemical reactions, allowing for the introduction of specific functionalities or structural changes to tailor the compound for desired applications. In addition, the trifluoromethyl group imparts increased metabolic stability to the resulting derivatives, enhancing their bioavailability and pharmacokinetic properties. Overall, the strategic incorporation of 2,2,2-Trifluoro-N-(hydroxymethyl)acetamide in chemical synthesis enables the efficient construction of diverse molecular scaffolds with improved pharmacological profiles and potential therapeutic benefits.