L-Proline, 4-cyclohexyl-, (4S)-


Chemical Name: L-Proline, 4-cyclohexyl-, (4S)-
CAS Number: 103201-78-1
Product Number: AG00389R(AGN-PC-0NVJTW)
Synonyms:
MDL No:
Molecular Formula: C11H19NO2
Molecular Weight: 197.2741

Identification/Properties


Computed Properties
Molecular Weight:
197.278g/mol
XLogP3:
0.3
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
3
Rotatable Bond Count:
2
Exact Mass:
197.142g/mol
Monoisotopic Mass:
197.142g/mol
Topological Polar Surface Area:
49.3A^2
Heavy Atom Count:
14
Formal Charge:
0
Complexity:
211
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
2
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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Chemical Structure



Trans-4-Cyclohexyl-L-Proline, also known as CHP, is a versatile compound widely used in chemical synthesis due to its unique chemical structure and properties. In organic chemistry, CHP serves as a valuable chiral building block for the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals. Its cyclic structure containing a proline moiety makes it an excellent precursor for the preparation of peptides and peptidomimetics with high stereochemical control. Additionally, CHP is commonly employed as a catalyst in asymmetric synthesis reactions to induce chirality in target molecules. Its cyclohexyl group provides steric hindrance, offering selectivity in reactions where stereochemistry is crucial. Overall, Trans-4-Cyclohexyl-L-Proline is an indispensable tool in the toolkit of synthetic chemists for achieving precise control over molecular structure and stereochemistry.