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Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

Uridine, 2'-deoxy-2',2'-difluoro-

OC[C@H]1O[C@H](C([C@@H]1O)(F)F)n1ccc(=O)[nH]c1=O Request for Quotation
Chemical Name: Uridine, 2'-deoxy-2',2'-difluoro-
CAS Number: 114248-23-6
Product Number: AG000AWJ(AGN-PC-0NYFED)
Synonyms:
MDL No:
Molecular Formula: C9H10F2N2O5
Molecular Weight: 264.1829

Identification/Properties

Computed Properties
Molecular Weight:
264.185g/mol
XLogP3:
-1.3
Hydrogen Bond Donor Count:
3
Hydrogen Bond Acceptor Count:
7
Rotatable Bond Count:
2
Exact Mass:
264.056g/mol
Monoisotopic Mass:
264.056g/mol
Topological Polar Surface Area:
99.1A^2
Heavy Atom Count:
18
Formal Charge:
0
Complexity:
414
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
3
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

GHS Pictogram:
Signal Word:
Warning
UN#:
-
Hazard Statements:
H315-H319-H335
Precautionary Statements:
P261-P305+P351+P338
Class:
-
Packing Group:
-

NMR Spectrum

Other Analytical Data

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Chemical Structure


2'-Deoxy-2',2'-difluorouridine, often referred to as DFUR, plays a crucial role in chemical synthesis as a versatile building block. This compound is utilized in the synthesis of nucleoside analogs, which are essential components in the development of antiviral and anticancer drugs. DFUR's unique fluorine substitution pattern confers distinct properties that enhance its effectiveness in inhibiting viral replication and cancer cell growth. Additionally, its compatibility with various chemical reactions and ability to be selectively modified make it a valuable tool in the construction of structurally diverse nucleoside analogs with enhanced pharmacological profiles.By serving as a key intermediate in chemical synthesis, 2'-Deoxy-2',2'-difluorouridine facilitates the creation of novel nucleoside analogs with improved bioavailability and target specificity. Its strategic incorporation into nucleotide sequences enables the generation of compounds with enhanced therapeutic benefits, making it a valuable asset in the development of next-generation pharmaceuticals.