N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodo-anilino)pyridine-4-carboxamide


Chemical Name: N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodo-anilino)pyridine-4-carboxamide
CAS Number: 1236699-92-5
Product Number: AG000KXC(AGN-PC-0O0O5K)
Synonyms:
MDL No:
Molecular Formula: C15H15FIN3O3
Molecular Weight: 431.2008

Identification/Properties


Computed Properties
Molecular Weight:
431.206g/mol
XLogP3:
1.7
Hydrogen Bond Donor Count:
4
Hydrogen Bond Acceptor Count:
6
Rotatable Bond Count:
6
Exact Mass:
431.014g/mol
Monoisotopic Mass:
431.014g/mol
Topological Polar Surface Area:
94.5A^2
Heavy Atom Count:
23
Formal Charge:
0
Complexity:
391
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
1
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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Chemical Structure



AS-703026 is a potent and selective inhibitor of JAK2 and FLT3 kinases, making it a valuable tool in chemical synthesis for targeting specific signaling pathways. This small molecule exhibits promising potential for use in the development of novel therapies for various diseases, particularly cancer, where dysregulated JAK-STAT and FLT3 signaling play a significant role. By effectively targeting these kinases, AS-703026 can help researchers explore new pathways for drug discovery and the development of precision medicines. Its unique mechanisms of action make it a versatile and valuable asset in the field of chemical synthesis, offering opportunities for innovative approaches to disease treatment and therapeutic intervention.