Arginine, N2-acetyl-


Chemical Name: Arginine, N2-acetyl-
CAS Number: 155-84-0
Product Number: AG001NJK(AGN-PC-0O4G1Q)
Synonyms:
MDL No:
Molecular Formula: C8H16N4O3
Molecular Weight: 216.2376

Identification/Properties


Properties
MP:
>215°C (dec.)
Storage:
Inert atmosphere;-10 ℃;
Form:
Solid
Computed Properties
Molecular Weight:
216.241g/mol
XLogP3:
-1.7
Hydrogen Bond Donor Count:
4
Hydrogen Bond Acceptor Count:
4
Rotatable Bond Count:
6
Exact Mass:
216.122g/mol
Monoisotopic Mass:
216.122g/mol
Topological Polar Surface Area:
131A^2
Heavy Atom Count:
15
Formal Charge:
0
Complexity:
261
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
1
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information


GHS Pictogram:
Signal Word:
Warning
UN#:
N/A
Hazard Statements:
H302-H315-H319-H335
Precautionary Statements:
P261-P305+P351+P338
Class:
N/A
Packing Group:
N/A

NMR Spectrum


Other Analytical Data


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Chemical Structure



Ac-Arg-OH, also known as N-Acetyl-L-arginine, is a key building block in chemical synthesis with versatile applications in the field of biochemistry and pharmaceutical research. This amino acid derivative plays a pivotal role as a crucial intermediate in the synthesis of various peptides and small molecules. In chemical synthesis, Ac-Arg-OH is commonly used as a protecting group for the arginine residue, enabling selective modification at specific positions within peptide sequences. Its acetyl moiety serves to shield the reactive alpha-amino group of arginine, preventing unwanted side reactions and facilitating controlled coupling reactions with other amino acids. Furthermore, Ac-Arg-OH can also function as a precursor for the synthesis of peptidomimetics and pharmaceutical compounds with enhanced stability and bioavailability. Its incorporation into peptide structures can impart improved resistance to enzymatic degradation and enhance the overall pharmacological properties of the final product.