D-Serine, O-(1,1-dimethylethyl)-


Chemical Name: D-Serine, O-(1,1-dimethylethyl)-
CAS Number: 18783-53-4
Product Number: AG002GIM(AGN-PC-0O5P3E)
Synonyms:
MDL No:
Molecular Formula: C7H15NO3
Molecular Weight: 161.1989

Identification/Properties


Computed Properties
Molecular Weight:
161.201g/mol
XLogP3:
-2.5
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
4
Rotatable Bond Count:
4
Exact Mass:
161.105g/mol
Monoisotopic Mass:
161.105g/mol
Topological Polar Surface Area:
72.6A^2
Heavy Atom Count:
11
Formal Charge:
0
Complexity:
139
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
1
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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NMR Spectrum


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Chemical Structure



H-D-Ser(tBu)-OH, also known as N-tert-butyloxycarbonyl-L-serine, is a valuable building block in chemical synthesis. This compound finds wide application in peptide synthesis as a protected form of serine amino acid. By utilizing H-D-Ser(tBu)-OH, chemists can incorporate serine residues into peptides with high specificity and efficiency. The tert-butyloxycarbonyl (tBu) protecting group enables selective deprotection under mild conditions, allowing for the synthesis of complex peptide structures. Additionally, H-D-Ser(tBu)-OH serves as a crucial component in the creation of bioactive peptides and pharmaceuticals, where precise control over the amino acid sequence is essential for desired biological activity. Its versatility and compatibility with standard peptide synthesis protocols make H-D-Ser(tBu)-OH a valuable tool for organic chemists working in the field of drug discovery and chemical biology.