Chemical Name: | D-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- |
CAS Number: | 84624-17-9 |
Product Number: | AG003QN8(AGN-PC-0OJ8RI) |
Synonyms: | |
MDL No: | |
Molecular Formula: | C20H21NO4 |
Molecular Weight: | 339.3850 |
Fmoc-D-Val-OH, also known as Fmoc-D-valine, is a key building block in chemical synthesis, particularly in solid-phase peptide synthesis. This compound plays a crucial role in peptide and protein synthesis by serving as a protected form of D-valine that can be easily incorporated into the peptide chain.In the process of solid-phase peptide synthesis, Fmoc-D-Val-OH is typically used as one of the amino acid building blocks that constitute the peptide sequence. The Fmoc (9-fluorenylmethyloxycarbonyl) protecting group temporarily shields the amine group of D-valine, allowing for selective deprotection during the assembly of the peptide chain on a solid support.Through a series of coupling, deprotection, and washing steps, Fmoc-D-Val-OH enables the stepwise elongation of the peptide chain, ultimately leading to the desired peptide or protein product. By controlling the sequence and positioning of Fmoc-D-Val-OH within the peptide sequence, chemists can precisely engineer peptides with specific structures and functions for various applications in biotechnology, pharmaceuticals, and biochemistry.