D-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-


Chemical Name: D-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
CAS Number: 84624-17-9
Product Number: AG003QN8(AGN-PC-0OJ8RI)
Synonyms:
MDL No:
Molecular Formula: C20H21NO4
Molecular Weight: 339.3850

Identification/Properties


Properties
MP:
143-144 °C(lit.);
Storage:
Keep in dry area;Room Temperature;
Form:
Solid
Computed Properties
Molecular Weight:
339.391g/mol
XLogP3:
4
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
4
Rotatable Bond Count:
6
Exact Mass:
339.147g/mol
Monoisotopic Mass:
339.147g/mol
Topological Polar Surface Area:
75.6A^2
Heavy Atom Count:
25
Formal Charge:
0
Complexity:
470
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
1
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information


GHS Pictogram:
Signal Word:
Warning
UN#:
N/A
Hazard Statements:
H302-H315-H319-H332-H335
Precautionary Statements:
P261-P280-P305+P351+P338
Class:
N/A
Packing Group:
N/A

NMR Spectrum


Other Analytical Data


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Chemical Structure



Fmoc-D-Val-OH, also known as Fmoc-D-valine, is a key building block in chemical synthesis, particularly in solid-phase peptide synthesis. This compound plays a crucial role in peptide and protein synthesis by serving as a protected form of D-valine that can be easily incorporated into the peptide chain.In the process of solid-phase peptide synthesis, Fmoc-D-Val-OH is typically used as one of the amino acid building blocks that constitute the peptide sequence. The Fmoc (9-fluorenylmethyloxycarbonyl) protecting group temporarily shields the amine group of D-valine, allowing for selective deprotection during the assembly of the peptide chain on a solid support.Through a series of coupling, deprotection, and washing steps, Fmoc-D-Val-OH enables the stepwise elongation of the peptide chain, ultimately leading to the desired peptide or protein product. By controlling the sequence and positioning of Fmoc-D-Val-OH within the peptide sequence, chemists can precisely engineer peptides with specific structures and functions for various applications in biotechnology, pharmaceuticals, and biochemistry.