Hydrazine, [4-(trifluoromethyl)phenyl]-, monohydrochloride


Chemical Name: Hydrazine, [4-(trifluoromethyl)phenyl]-, monohydrochloride
CAS Number: 2923-56-0
Product Number: AG002XSB(AGN-PC-0R4WIG)
Synonyms:
MDL No:
Molecular Formula: C7H8ClF3N2
Molecular Weight: 212.6000

Identification/Properties


Properties
MP:
200 °C
BP:
230 °C at 760 mmHg
Storage:
Room Temperature;
Form:
Solid
Computed Properties
Molecular Weight:
212.6g/mol
Hydrogen Bond Donor Count:
3
Hydrogen Bond Acceptor Count:
5
Rotatable Bond Count:
1
Exact Mass:
212.033g/mol
Monoisotopic Mass:
212.033g/mol
Topological Polar Surface Area:
38A^2
Heavy Atom Count:
13
Formal Charge:
0
Complexity:
138
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
2
Compound Is Canonicalized:
Yes

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NMR Spectrum


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Chemical Structure



4-(Trifluoromethyl)Phenylhydrazine Hydrochloride, a versatile reagent in chemical synthesis, serves as a pivotal building block in various reactions. In the field of medicinal chemistry, it is commonly used for the synthesis of biologically active compounds due to its ability to introduce the trifluoromethyl group into organic molecules. Additionally, this compound plays a crucial role in the preparation of pharmaceuticals, agrochemicals, and other fine chemicals by facilitating key reactions such as nucleophilic substitution, condensation, and formation of azo compounds. Its unique structural features make it a valuable tool for synthetic chemists looking to modify aromatic systems and enhance the physicochemical properties of their target molecules. This reagent's strong nucleophilic and electrophilic character makes it a valuable asset in the development of new chemical entities with improved biological activities and enhanced drug-like properties.