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Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

2-Methoxy-6-trifluoromethylpyridine-4-boronic acid, pinacol ester

COc1cc(cc(n1)C(F)(F)F)B1OC(C(O1)(C)C)(C)C Request for Quotation
Chemical Name: 2-Methoxy-6-trifluoromethylpyridine-4-boronic acid, pinacol ester
CAS Number: 1150561-66-2
Product Number: AG000FSZ(AGN-PC-0WA6W2)
Synonyms:
MDL No:
Molecular Formula: C13H17BF3NO3
Molecular Weight: 303.0852

Identification/Properties

Properties
Storage:
Inert atmosphere;-10 ℃;
Form:
Solid
Computed Properties
Molecular Weight:
303.088g/mol
Hydrogen Bond Donor Count:
0
Hydrogen Bond Acceptor Count:
7
Rotatable Bond Count:
2
Exact Mass:
303.125g/mol
Monoisotopic Mass:
303.125g/mol
Topological Polar Surface Area:
40.6A^2
Heavy Atom Count:
21
Formal Charge:
0
Complexity:
373
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

GHS Pictogram:
Signal Word:
Warning
UN#:
-
Hazard Statements:
H302-H315-H319-H335
Precautionary Statements:
P261-P280-P301+P312-P302+P352-P305+P351+P338
Class:
-
Packing Group:
-

NMR Spectrum

Other Analytical Data

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Chemical Structure


2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine is a versatile compound frequently utilized in chemical synthesis. Its unique structure, incorporating both boron and fluorine moieties, makes it a valuable building block in the preparation of various organic molecules. One key application of 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine is in cross-coupling reactions, particularly in metal-catalyzed Suzuki-Miyaura coupling reactions. In this process, the compound acts as a boron source, enabling the formation of carbon-carbon bonds between the aromatic pyridine ring and other organic substrates. This reaction is widely employed in the synthesis of pharmaceuticals, agrochemicals, and materials science.Furthermore, the trifluoromethyl group present in the molecule enhances its lipophilicity and metabolic stability, making it a valuable tool in medicinal chemistry for the development of novel bioactive compounds. Overall, 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine is a pivotal reagent in modern organic synthesis, facilitating the construction of complex molecules with diverse applications.