4-FMOC-PIPERAZINE-2-(R)-CARBOXYLIC ACID


Chemical Name: 4-FMOC-PIPERAZINE-2-(R)-CARBOXYLIC ACID
CAS Number: 747393-31-3
Product Number: AG005HXD(AGN-PC-0WAAG1)
Synonyms:
MDL No:
Molecular Formula: C20H20N2O4
Molecular Weight: 352.3838

Identification/Properties


Properties
BP:
580.4±50.0°C at 760 mmHg
Storage:
Keep in dry area;2-8℃;

Safety Information


GHS Pictogram:
Signal Word:
Warning
UN#:
N/A
Hazard Statements:
H302-H315-H319-H335
Precautionary Statements:
P261-P305+P351+P338
Class:
N/A
Packing Group:
N/A

NMR Spectrum


Other Analytical Data


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Chemical Structure



$Name$ is a versatile compound widely used in chemical synthesis, particularly in peptide chemistry. As a derivative of piperazine with a 4-fluorenylmethyloxycarbonyl (Fmoc) protecting group attached to the piperazine nitrogen atom and an (R)-carboxylic acid moiety, this compound plays a crucial role in the synthesis of peptides and peptidomimetics.One of the key applications of 4-Fmoc-piperazine-2-(R)-carboxylic acid is as a building block in solid-phase peptide synthesis (SPPS). In this process, the Fmoc group serves as a temporary protecting group for the piperazine nitrogen, allowing for selective deprotection and subsequent elongation of the peptide chain. The presence of the (R)-carboxylic acid functionality enables the coupling of this compound with amino acids or other peptide fragments, facilitating the stepwise assembly of the desired peptide sequence.Additionally, 4-Fmoc-piperazine-2-(R)-carboxylic acid can be used in the synthesis of peptidomimetics, which are non-peptide molecules designed to mimic the structure and/or function of peptides. By incorporating this compound into the backbone of peptidomimetics, researchers can modulate the properties of these molecules to achieve specific biological activities or improve their pharmacokinetic profiles.Overall, the unique structural features of 4-Fmoc-piperazine-2-(R)-carboxylic acid make it a valuable tool in chemical synthesis, particularly in the synthesis of peptides and peptidomimetics for various biomedical applications.