Chemical Name: | 5-(cyclopropylethynyl)pyridin-3-ylboronic acid |
CAS Number: | 1189372-89-1 |
Product Number: | AG0039JW(AGN-PC-0WAAU5) |
Synonyms: | |
MDL No: | |
Molecular Formula: | C10H10BNO2 |
Molecular Weight: | 187.0029 |
5-(Cyclopropylethynyl)pyridin-3-ylboronic acid is a versatile chemical reagent commonly utilized in organic synthesis for its unique properties and reactivity. This compound serves as a valuable building block in the construction of various organic molecules, particularly in the field of medicinal chemistry and drug development.One of the key applications of 5-(Cyclopropylethynyl)pyridin-3-ylboronic acid is its role as a potent and selective Suzuki-Miyaura coupling partner. This reaction, catalyzed by palladium, enables the cross-coupling of the boronic acid moiety with a diverse range of aryl halides or pseudohalides. This versatile coupling reaction allows for the rapid and efficient assembly of complex molecular structures, making it a powerful tool in the synthesis of pharmaceuticals, agrochemicals, and materials science.Additionally, 5-(Cyclopropylethynyl)pyridin-3-ylboronic acid can participate in various other transformations such as Sonogashira coupling, Heck reactions, and other C-C bond-forming reactions. Its unique cyclopropyl-ethynyl substitution pattern imparts distinct steric and electronic properties to the molecule, influencing its reactivity and selectivity in a synthetic context.Overall, 5-(Cyclopropylethynyl)pyridin-3-ylboronic acid is a valuable reagent in chemical synthesis, offering chemists a powerful tool for the construction of complex organic molecules with potential applications in drug discovery and development.