5-(cyclopropylethynyl)pyridin-3-ylboronic acid


Chemical Name: 5-(cyclopropylethynyl)pyridin-3-ylboronic acid
CAS Number: 1189372-89-1
Product Number: AG0039JW(AGN-PC-0WAAU5)
Synonyms:
MDL No:
Molecular Formula: C10H10BNO2
Molecular Weight: 187.0029

Identification/Properties


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GHS Pictogram:
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UN#:
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Hazard Statements:
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Class:
-
Packing Group:
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NMR Spectrum


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Chemical Structure



5-(Cyclopropylethynyl)pyridin-3-ylboronic acid is a versatile chemical reagent commonly utilized in organic synthesis for its unique properties and reactivity. This compound serves as a valuable building block in the construction of various organic molecules, particularly in the field of medicinal chemistry and drug development.One of the key applications of 5-(Cyclopropylethynyl)pyridin-3-ylboronic acid is its role as a potent and selective Suzuki-Miyaura coupling partner. This reaction, catalyzed by palladium, enables the cross-coupling of the boronic acid moiety with a diverse range of aryl halides or pseudohalides. This versatile coupling reaction allows for the rapid and efficient assembly of complex molecular structures, making it a powerful tool in the synthesis of pharmaceuticals, agrochemicals, and materials science.Additionally, 5-(Cyclopropylethynyl)pyridin-3-ylboronic acid can participate in various other transformations such as Sonogashira coupling, Heck reactions, and other C-C bond-forming reactions. Its unique cyclopropyl-ethynyl substitution pattern imparts distinct steric and electronic properties to the molecule, influencing its reactivity and selectivity in a synthetic context.Overall, 5-(Cyclopropylethynyl)pyridin-3-ylboronic acid is a valuable reagent in chemical synthesis, offering chemists a powerful tool for the construction of complex organic molecules with potential applications in drug discovery and development.