5-Fluoro-7-azaindole-3-carboxylic acid


Chemical Name: 5-Fluoro-7-azaindole-3-carboxylic acid
CAS Number: 1067193-34-3
Product Number: AG008XQH(AGN-PC-0WABFF)
Synonyms:
MDL No:
Molecular Formula: C8H5FN2O2
Molecular Weight: 180.1359

Identification/Properties


Computed Properties
Molecular Weight:
180.138g/mol
XLogP3:
0.9
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
4
Rotatable Bond Count:
1
Exact Mass:
180.034g/mol
Monoisotopic Mass:
180.034g/mol
Topological Polar Surface Area:
66A^2
Heavy Atom Count:
13
Formal Charge:
0
Complexity:
224
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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Chemical Structure



5-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid is a valuable compound widely used in chemical synthesis as a key building block for the preparation of various biologically active molecules. Its unique structure and reactivity make it an ideal intermediate in the synthesis of pharmaceuticals, agrochemicals, and materials.This compound serves as a versatile starting material for the synthesis of heterocyclic compounds and complex organic molecules. Its fluorine substituent enhances the compound's reactivity and can serve as a handle for further functionalization. By incorporating this acid into chemical reactions, chemists can introduce fluorine atoms into target molecules, which can significantly impact their biological activity or physicochemical properties.Moreover, the pyrrolo[2,3-b]pyridine core structure of this compound is found in many natural products and biologically active molecules, making it a valuable scaffold for drug discovery and development. Chemists can modify this core structure through various chemical transformations to create new compounds with potentially improved pharmacological properties.Overall, the application of 5-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid in chemical synthesis enables the efficient and strategic construction of structurally diverse molecules with potential applications in the fields of medicine, agriculture, and materials science. Its role as a versatile building block underscores its importance in the synthesis of valuable compounds for various industrial and academic research purposes.