DL-3,5-Difluorophenylalanine


Chemical Name: DL-3,5-Difluorophenylalanine
CAS Number: 32133-37-2
Product Number: AG003PT0(AGN-PC-0WACX8)
Synonyms:
MDL No:
Molecular Formula: C9H9F2NO2
Molecular Weight: 201.1701

Identification/Properties


Properties
MP:
269.5-273.5 °C(lit.)
BP:
295.1°C at 760 mmHg
Storage:
Keep in dry area;Room Temperature;
Form:
Solid
Computed Properties
Molecular Weight:
201.173g/mol
XLogP3:
-1.2
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
5
Rotatable Bond Count:
3
Exact Mass:
201.06g/mol
Monoisotopic Mass:
201.06g/mol
Topological Polar Surface Area:
63.3A^2
Heavy Atom Count:
14
Formal Charge:
0
Complexity:
203
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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NMR Spectrum


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Chemical Structure



3,5-Difluorophenylalanine is a versatile compound widely utilized in chemical synthesis for the creation of novel pharmaceuticals and agrochemicals. Its unique structure, with fluorine atoms positioned at the 3rd and 5th positions on the phenylalanine ring, imparts distinct properties that can be harnessed in various synthetic processes.In organic chemistry, 3,5-Difluorophenylalanine serves as a valuable building block for the synthesis of peptide analogs and structurally modified amino acids. By incorporating this compound into peptide chains, researchers can enhance biological activity, improve stability, and enhance selectivity of the resulting molecules. This makes 3,5-Difluorophenylalanine particularly useful in the design and development of new drug candidates with improved pharmacological profiles.Furthermore, the presence of fluorine atoms in 3,5-Difluorophenylalanine can facilitate medicinal chemistry studies by providing unique spectroscopic and physicochemical properties that aid in compound characterization and validation. These attributes make it a valuable tool for drug discovery and development efforts aimed at addressing unmet medical needs and improving therapeutic outcomes.Overall, 3,5-Difluorophenylalanine plays a crucial role in advancing the field of chemical synthesis, particularly in the context of drug design and discovery. Its versatility and distinctive properties make it an indispensable component in the toolkit of synthetic chemists working to develop innovative solutions for complex biological and pharmaceutical challenges.