cis-1-Boc-3-fluoro-4-hydroxypiperidine


Chemical Name: cis-1-Boc-3-fluoro-4-hydroxypiperidine
CAS Number: 955028-88-3
Product Number: AG00IJ5Q(AGN-PC-0WAFNY)
Synonyms:
MDL No:
Molecular Formula:
Molecular Weight:

Identification/Properties


Computed Properties
Molecular Weight:
219.256g/mol
XLogP3:
1
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
4
Rotatable Bond Count:
2
Exact Mass:
219.127g/mol
Monoisotopic Mass:
219.127g/mol
Topological Polar Surface Area:
49.8A^2
Heavy Atom Count:
15
Formal Charge:
0
Complexity:
239
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
2
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information


GHS Pictogram:
Signal Word:
Warning
UN#:
N/A
Hazard Statements:
H302-H315-H319-H335
Precautionary Statements:
P261-P305+P351+P338
Class:
N/A
Packing Group:
N/A

NMR Spectrum


Other Analytical Data


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Chemical Structure



The cis-tert-Butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate is a versatile compound employed in chemical synthesis for its unique structural features and reactivity. This compound serves as a valuable building block in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals due to its distinct stereochemistry and functional groups.1. As a key intermediate in drug development: The cis-tert-Butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate plays a crucial role in the synthesis of pharmaceutical compounds. Its specific structure enables the introduction of fluorine and hydroxyl functionalities into the target molecules, enhancing their biological activity and pharmacokinetic properties. This compound is utilized in the preparation of potential anticancer agents, antiviral drugs, and other therapeutic agents.2. In the synthesis of agrochemicals: In the field of agrochemistry, cis-tert-Butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate is utilized for the construction of pesticides, herbicides, and fungicides. By incorporating the fluorine and hydroxyl groups into the molecular structure, this compound can enhance the potency and selectivity of the agrochemical products. Its application in agrochemical synthesis contributes to the development of effective and environmentally friendly crop protection agents.3. Utilization in the production of fine chemicals: Moreover, cis-tert-Butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate serves as a valuable precursor in the synthesis of various fine chemicals. Its unique stereochemistry and reactivity allow for the efficient construction of complex molecular scaffolds and functionalized compounds. This compound is employed in the development of specialty chemicals, flavoring agents, and other high-value products with diverse applications in industries ranging from cosmetics to materials science.In summary, the cis-tert-Butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate plays a pivotal role in chemical synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and fine chemicals. Its distinctive properties make it a valuable tool for researchers and scientists engaged in the design and production of novel compounds with potent biological activities and industrial applications.