2-METHYL-3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-BENZENESULFONAMIDE


Chemical Name: 2-METHYL-3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-BENZENESULFONAMIDE
CAS Number: 1261295-10-6
Product Number: AG000RPQ(AGN-PC-0WAFOT)
Synonyms:
MDL No:
Molecular Formula: C13H20BNO4S
Molecular Weight: 297.1782

Identification/Properties


Properties
Storage:
Inert atmosphere;2-8℃;
Form:
Solid
Computed Properties
Molecular Weight:
297.176g/mol
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
5
Rotatable Bond Count:
2
Exact Mass:
297.121g/mol
Monoisotopic Mass:
297.121g/mol
Topological Polar Surface Area:
87A^2
Heavy Atom Count:
20
Formal Charge:
0
Complexity:
455
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information


NMR Spectrum


Other Analytical Data


Request for Quotation


Customer Feedback


Chemical Structure



2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide, commonly known as $name$, is a versatile compound widely used in chemical synthesis. This compound plays a crucial role as a key building block in the construction of various organic molecules due to its unique structural properties.The functional groups present in $name$ make it a valuable reagent in Suzuki-Miyaura cross-coupling reactions. In this reaction, $name$ acts as a boronic acid derivative, facilitating the formation of carbon-carbon bonds between aryl or vinyl halides and aryl or alkenyl boronic acids. This important synthetic strategy allows for the efficient synthesis of biaryl compounds, which are prevalent in pharmaceuticals, agrochemicals, and materials science.Moreover, the sulfonamide group in $name$ can serve as a directing group in transition-metal-catalyzed C-H activation reactions. This capability enables selective functionalization of aromatic C-H bonds, offering a powerful tool for the regioselective modification of complex molecules. By leveraging the reactivity of the sulfonamide moiety, chemists can streamline the synthesis of structurally diverse organic compounds with high efficiency and precision.In summary, the application of 2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide in chemical synthesis highlights its importance as a versatile and indispensable reagent for the construction of complex organic molecules with strategic bond formations.