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Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

(2R)-2-(2,5-difluorophenyl)pyrrolidine HCl

Fc1ccc(c(c1)[C@H]1CCCN1)F Request for Quotation
Chemical Name: (2R)-2-(2,5-difluorophenyl)pyrrolidine HCl
CAS Number: 1218935-59-1
Product Number: AG0016C2(AGN-PC-0WAFPX)
Synonyms:
MDL No:
Molecular Formula: C10H11F2N
Molecular Weight: 183.1978

Identification/Properties

Computed Properties
Molecular Weight:
183.202g/mol
XLogP3:
2
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
3
Rotatable Bond Count:
1
Exact Mass:
183.086g/mol
Monoisotopic Mass:
183.086g/mol
Topological Polar Surface Area:
12A^2
Heavy Atom Count:
13
Formal Charge:
0
Complexity:
174
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
1
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

GHS Pictogram:
Signal Word:
Warning
UN#:
N/A
Hazard Statements:
H302-H315-H319-H335
Precautionary Statements:
P261-P305+P351+P338
Class:
N/A
Packing Group:
N/A

NMR Spectrum

Other Analytical Data

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Chemical Structure


(R)-2-(2,5-Difluorophenyl)pyrrolidine is a valuable chiral building block widely utilized in chemical synthesis processes. Its unique stereochemistry and fluorine substitution pattern impart distinctive properties that make it a versatile intermediate in the production of pharmaceuticals, agrochemicals, and materials. In asymmetric synthesis, this compound serves as a key precursor for constructing various biologically active molecules with high enantioselectivity. Additionally, its fluorinated phenyl group enhances the compound's lipophilicity and bioavailability, making it an attractive candidate for drug design and development. The incorporation of (R)-2-(2,5-Difluorophenyl)pyrrolidine in synthetic routes enables the creation of complex molecular architectures with precise stereochemical control, facilitating the production of diverse compounds for a range of applications.