Fmoc-Arg(Pbf)-OH (U-13C6, U-15N4) is a specialized amino acid derivative that finds extensive utility in chemical synthesis. This high-quality compound is specifically designed for use in peptide synthesis, where precise isotope labeling is crucial for various applications. By incorporating uniformly carbon-13 and nitrogen-15 labeled arginine with Fmoc (fluorenylmethoxycarbonyl) and Pbf (2,2,4,6,7-pentamethyldihydrobenzofurane-5-sulfonyl) protecting groups, this compound offers researchers a powerful tool for the production of labeled peptides.The incorporation of stable isotopes in peptides synthesized using Fmoc-Arg(Pbf)-OH (U-13C6, U-15N4) enables researchers to conduct advanced studies in structural biology, biomolecular NMR spectroscopy, and mass spectrometry. Specifically, the uniform labeling of arginine with carbon-13 and nitrogen-15 facilitates precise tracking and characterization of peptides within complex biological systems. This is essential for elucidating protein structures, investigating protein-protein interactions, and studying metabolic pathways.Overall, Fmoc-Arg(Pbf)-OH (U-13C6, U-15N4) serves as a versatile building block for the synthesis of isotopically labeled peptides with enhanced sensitivity and resolution. Researchers in the fields of biochemistry, pharmaceuticals, and biotechnology can leverage the unique properties of this compound to advance their understanding of biological processes and develop innovative solutions for various scientific challenges.
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