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Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

2-Trifluoromethylthiazole-5-carboxylic acid ethyl ester

CCOC(=O)c1cnc(s1)C(F)(F)F Request for Quotation
Chemical Name: 2-Trifluoromethylthiazole-5-carboxylic acid ethyl ester
CAS Number: 131748-96-4
Product Number: AG000ZOP(AGN-PC-00427F)
Synonyms:
MDL No:
Molecular Formula: C7H6F3NO2S
Molecular Weight: 225.1882

Identification/Properties

Computed Properties
Molecular Weight:
225.185g/mol
XLogP3:
2.4
Hydrogen Bond Donor Count:
0
Hydrogen Bond Acceptor Count:
7
Rotatable Bond Count:
3
Exact Mass:
225.007g/mol
Monoisotopic Mass:
225.007g/mol
Topological Polar Surface Area:
67.4A^2
Heavy Atom Count:
14
Formal Charge:
0
Complexity:
222
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

GHS Pictogram:
Signal Word:
Warning
UN#:
N/A
Hazard Statements:
H227-H302-H315-H317-H319-H335
Precautionary Statements:
P210-P261-P280-P305+P351+P338
Class:
N/A
Packing Group:
N/A

NMR Spectrum

Other Analytical Data

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Chemical Structure


Ethyl 2-(trifluoromethyl)thiazole-5-carboxylate is a versatile compound that finds extensive applications in chemical synthesis. This compound is commonly used as a key building block in the creation of various pharmaceuticals, agrochemicals, and advanced materials due to its unique structural properties.In chemical synthesis, Ethyl 2-(trifluoromethyl)thiazole-5-carboxylate serves as a valuable precursor for the preparation of diverse thiazole derivatives. Its trifluoromethyl group imparts enhanced physicochemical properties to the final products, such as increased lipophilicity and metabolic stability, making it particularly useful in drug discovery and development. Additionally, the thiazole ring structure of this compound is known to exhibit biological activities, making it an essential component in the synthesis of bioactive molecules.Furthermore, Ethyl 2-(trifluoromethyl)thiazole-5-carboxylate can participate in various synthetic transformations, such as cross-coupling reactions, nucleophilic substitutions, and heterocycle formation, allowing for the construction of complex molecular scaffolds with high efficiency. Its presence in the synthesis of intricate organic compounds highlights its significance in modern chemical research and industrial applications.