Chemical Name: | chlorozinc(1+);1-methanidyl-3-(trifluoromethyl)benzene |
CAS Number: | 480438-42-4 |
Product Number: | AG00DF3U(AGN-PC-0053XI) |
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MDL No: | |
Molecular Formula: | C8H6ClF3Zn |
Molecular Weight: | 259.9614496 |
Chloro[[3-(trifluoromethyl)phenyl]methyl]zinc serves as a versatile reagent in the field of chemical synthesis, offering a wide array of applications. This organozinc compound can participate in various reactions, including cross-coupling reactions commonly used for the construction of carbon-carbon bonds.In organic synthesis, Chloro[[3-(trifluoromethyl)phenyl]methyl]zinc is often employed in palladium-catalyzed coupling reactions to introduce the phenyltrifluoromethyl moiety onto target molecules. This enables the synthesis of diverse organic compounds with enhanced chemical properties, such as increased lipophilicity and metabolic stability. Additionally, the trifluoromethyl group can impart unique electronic effects, influencing the reactivity and properties of the resulting molecules.Furthermore, Chloro[[3-(trifluoromethyl)phenyl]methyl]zinc can be utilized in the preparation of pharmaceutical intermediates, agrochemicals, and functional materials. Its compatibility with a range of functional groups and its ability to undergo selective transformations make it a valuable tool for synthetic chemists seeking to access complex molecular architectures in a controlled manner.