(2R,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-2-carboxylic acid


Chemical Name: (2R,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-2-carboxylic acid
CAS Number: 917835-93-9
Product Number: AG00360Y(AGN-PC-00HOMM)
Synonyms:
MDL No:
Molecular Formula: C11H19NO5
Molecular Weight: 245.2723

Identification/Properties


Properties
Storage:
Keep in dry area;2-8℃;
Form:
Solid
Computed Properties
Molecular Weight:
245.275g/mol
XLogP3:
0.6
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
5
Rotatable Bond Count:
3
Exact Mass:
245.126g/mol
Monoisotopic Mass:
245.126g/mol
Topological Polar Surface Area:
87.1A^2
Heavy Atom Count:
17
Formal Charge:
0
Complexity:
310
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
2
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information


NMR Spectrum


Other Analytical Data


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Chemical Structure



1-(tert-Butoxycarbonyl)-4-hydroxypiperidine-2-carboxylic acid is a versatile compound widely utilized in chemical synthesis for its unique properties and reactivity. This compound serves as a crucial building block in the preparation of various pharmaceuticals, agrochemicals, and specialty chemicals due to its ability to undergo selective functional group transformations.In organic synthesis, 1-(tert-Butoxycarbonyl)-4-hydroxypiperidine-2-carboxylic acid acts as a key precursor for the introduction of the tert-butoxycarbonyl (Boc) protecting group, which plays a pivotal role in controlling regioselectivity and enhancing the stability of sensitive functional groups during multi-step synthetic processes. Moreover, the hydroxyl and carboxylic acid moieties present in this compound enable facile derivatization leading to the synthesis of diverse analogs and derivatives with tailored properties.Furthermore, the incorporation of 1-(tert-Butoxycarbonyl)-4-hydroxypiperidine-2-carboxylic acid into organic reactions allows for the construction of complex molecular architectures with high stereochemical control. This compound's structural features and reactivity profiles make it a valuable asset in the assembly of bioactive compounds and natural product analogs with significant pharmacological potential.Overall, the strategic utilization of 1-(tert-Butoxycarbonyl)-4-hydroxypiperidine-2-carboxylic acid in chemical synthesis showcases its pivotal role in facilitating the efficient and precise construction of molecular entities with a wide range of applications across the chemical industry.