3-Pyridinamine, 6-chloro-5-(trifluoromethyl)-


Chemical Name: 3-Pyridinamine, 6-chloro-5-(trifluoromethyl)-
CAS Number: 99368-68-0
Product Number: AG005SDM(AGN-PC-00MXYO)
Synonyms:
MDL No:
Molecular Formula: C6H4ClF3N2
Molecular Weight: 196.5576

Identification/Properties


Properties
BP:
292°C at 760 mmHg
Storage:
Inert atmosphere;2-8℃;
Form:
Solid
Computed Properties
Molecular Weight:
196.557g/mol
XLogP3:
2
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
5
Rotatable Bond Count:
0
Exact Mass:
196.002g/mol
Monoisotopic Mass:
196.002g/mol
Topological Polar Surface Area:
38.9A^2
Heavy Atom Count:
12
Formal Charge:
0
Complexity:
161
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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NMR Spectrum


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Chemical Structure



6-Chloro-5-(trifluoromethyl)pyridin-3-amine is a versatile compound widely utilized in chemical synthesis as a key building block. With its unique structure and functional groups, this compound plays a crucial role in the creation of various pharmaceuticals, agrochemicals, and specialty chemicals. Its presence in synthetic pathways enables the introduction of specific functionalities, such as halogens and trifluoromethyl groups, into target molecules, enhancing their biological activity or physicochemical properties. The 6-Chloro-5-(trifluoromethyl)pyridin-3-amine is particularly valued for its ability to serve as a starting material for the preparation of more complex molecules through diverse synthetic methodologies, including cross-coupling reactions, nucleophilic substitution, and transition-metal-catalyzed transformations. Its strategic placement within a molecule allows for precise modification and fine-tuning of molecular properties, making it a valuable tool for chemical synthesis in both academic research and industrial applications.