[2-(difluoromethoxy)phenyl]boronic acid


Chemical Name: [2-(difluoromethoxy)phenyl]boronic acid
CAS Number: 947533-11-1
Product Number: AG0036RE(AGN-PC-06GMHH)
Synonyms:
MDL No:
Molecular Formula: C7H7BF2O3
Molecular Weight: 187.9365

Identification/Properties


Properties
Storage:
-10 ℃;

Safety Information


NMR Spectrum


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Chemical Structure



The application of (2-(Difluoromethoxy)phenyl)boronic acid in chemical synthesis is highly versatile and valuable. This compound, with its unique difluoromethoxy functional group attached to a phenylboronic acid framework, serves as a key building block in organic chemistry. (2-(Difluoromethoxy)phenyl)boronic acid is commonly used in Suzuki-Miyaura cross-coupling reactions, where it acts as a boronate ester in the presence of a palladium catalyst to form carbon-carbon bonds. This reaction is crucial for creating complex organic molecules in pharmaceuticals, agrochemicals, and materials science.Additionally, (2-(Difluoromethoxy)phenyl)boronic acid can participate in other important transformations such as halogenation, arylation, and cyanation reactions. Its difluoromethoxy group enhances the electronic and steric properties of the compound, making it particularly useful in medicinal chemistry for designing bioactive molecules with improved properties.Overall, (2-(Difluoromethoxy)phenyl)boronic acid is a powerful tool in the hands of synthetic chemists, enabling the efficient construction of diverse chemical structures with broad applications in various industries.