tert-butyl 6-bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole-1-carboxylate|1218790-27-2,AngeneChemical

Contact Angene

Tel: +852 8191 6999

Email: [email protected]

Pyrimidine, 5-bromo-2-methyl-

1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide

2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-

O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]

Tris(dibenzylideneacetone)dipalladium

C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C

Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

tert-butyl 6-bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole-1-carboxylate

Brc1ccc2c(c1)n(cc2B1OC(C(O1)(C)C)(C)C)C(=O)OC(C)(C)C

Request for Quotation

Chemical Name:	tert-butyl 6-bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole-1-carboxylate
CAS Number:	1218790-27-2
Product Number:	AG001690(AGN-PC-09PZLY)
Synonyms:
MDL No:
Molecular Formula:	C19H25BBrNO4
Molecular Weight:	422.1211

Identification/Properties
Safety Information
NMR Spectrum
Other Analytical Data
Customer Feedback

Identification/Properties

Properties

Storage:

Keep in dry area;2-8℃;

Form:

Solid

Computed Properties

Molecular Weight:

422.126g/mol

Hydrogen Bond Donor Count:

Hydrogen Bond Acceptor Count:

Rotatable Bond Count:

Exact Mass:

421.106g/mol

Monoisotopic Mass:

421.106g/mol

Topological Polar Surface Area:

49.7A^2

Heavy Atom Count:

Formal Charge:

Complexity:

546

Isotope Atom Count:

Defined Atom Stereocenter Count:

Undefined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Undefined Bond Stereocenter Count:

Covalently-Bonded Unit Count:

Compound Is Canonicalized:

Yes

Safety Information

GHS Pictogram:

N/A

Signal Word:

UN#:

Hazard Statements:

Precautionary Statements:

Class:

Packing Group:

NMR Spectrum

Other Analytical Data

Request for Quotation

Quantity Required:*

Company Name:

Contact Person:*

Email:*

Tel:*

Country:*

Others:(Optional)

Verification Code:

Customer Feedback

Chemical Structure

1H-Indole-1-carboxylic acid, 6-bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl ester is a versatile compound commonly used in chemical synthesis as a key building block. Due to its unique structure and reactivity, this compound serves as a valuable intermediate in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals. Its functional groups can participate in a wide range of reactions, including cross-coupling reactions, nucleophilic substitutions, and heterocyclic formation.In the realm of drug discovery and development, this compound has found application in the synthesis of novel drug candidates and potential pharmacophores. Its bromo and boron functionalities enable strategic transformations, such as Suzuki-Miyaura couplings, to introduce diverse substitution patterns onto the indole core. Additionally, the 1,1-dimethylethyl ester moiety provides stability and can be selectively removed under mild conditions to reveal the free carboxylic acid group, allowing for further derivatization.Overall, the strategic placement of functional groups in 1H-Indole-1-carboxylic acid, 6-bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl ester makes it a valuable intermediate for the synthesis of complex molecules, making it an indispensable tool in the arsenal of synthetic chemists.