N-[1-[(2S,4R,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide


Chemical Name: N-[1-[(2S,4R,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
CAS Number: 102212-98-6
Product Number: AG0006Y6(AGN-PC-0BIS50)
Synonyms:
MDL No: MFCD00036315
Molecular Formula: C46H52N5O8P
Molecular Weight: 833.9075

Identification/Properties


Computed Properties
Molecular Weight:
833.923g/mol
XLogP3:
7.3
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
10
Rotatable Bond Count:
19
Exact Mass:
833.355g/mol
Monoisotopic Mass:
833.355g/mol
Topological Polar Surface Area:
144A^2
Heavy Atom Count:
60
Formal Charge:
0
Complexity:
1440
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
3
Undefined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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Chemical Structure



DMT-dC(bz)Phosphoramidite is a valuable tool in chemical synthesis, specifically in the field of nucleic acid synthesis. This phosphoramidite derivative serves as a key building block for the efficient and controlled assembly of DNA strands. By incorporating the DMT (dimethoxytrityl) protecting group, this phosphoramidite ensures the selective and reliable addition of deoxycytidine (dC) residues, leading to the precise construction of DNA sequences. The benzoyl (bz) group provides additional stability and protection during the synthesis process, enhancing the overall efficiency and yield of the nucleic acid synthesis. With its carefully designed chemical structure, DMT-dC(bz)Phosphoramidite enables researchers to synthesize high-quality DNA oligonucleotides with accuracy and reproducibility, making it an indispensable reagent for the synthesis of customized DNA sequences for various applications in molecular biology and biotechnology.