8-bromoquinazolin-4-amine


Chemical Name: 8-bromoquinazolin-4-amine
CAS Number: 1260657-19-9
Product Number: AG000QYV(AGN-PC-0H0YMX)
Synonyms:
MDL No:
Molecular Formula: C8H6BrN3
Molecular Weight: 224.0573

Identification/Properties


Computed Properties
Molecular Weight:
224.061g/mol
XLogP3:
1.9
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
3
Rotatable Bond Count:
0
Exact Mass:
222.975g/mol
Monoisotopic Mass:
222.975g/mol
Topological Polar Surface Area:
51.8A^2
Heavy Atom Count:
12
Formal Charge:
0
Complexity:
164
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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NMR Spectrum


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Chemical Structure



$Name$ is a versatile compound that plays a crucial role in chemical synthesis, particularly in the field of medicinal chemistry. This product, 8-Bromoquinazolin-4-amine, serves as a key building block in the creation of various pharmaceutical compounds and organic molecules. By incorporating this compound into synthetic pathways, chemists can access a wide range of structurally diverse molecules with potential therapeutic applications.Specifically, 8-Bromoquinazolin-4-amine is utilized as a valuable intermediate in the synthesis of biologically active compounds, including kinase inhibitors, anticancer agents, and pharmaceutical drugs. Its unique structure and reactivity make it a valuable tool in the development of novel molecules with enhanced pharmacological properties. Chemists often leverage the versatility of this compound to introduce specific functional groups or modifications that can improve the potency, selectivity, or bioavailability of the final compound.Moreover, the presence of the bromo and amino groups in 8-Bromoquinazolin-4-amine allows for further derivatization through diverse chemical transformations, such as nucleophilic substitution, Suzuki coupling, or reductive amination. This flexibility in chemical modification enables researchers to fine-tune the physicochemical properties of the target molecules, leading to potential drug candidates with improved efficacy and safety profiles.Overall, the strategic incorporation of 8-Bromoquinazolin-4-amine in chemical synthesis opens up new avenues for the design and development of bioactive compounds with therapeutic potential, making it a valuable tool for medicinal chemists and researchers in the pharmaceutical industry.