4(5H)-Thiazolone, 2-amino-5-methyl-


Chemical Name: 4(5H)-Thiazolone, 2-amino-5-methyl-
CAS Number: 3805-14-9
Product Number: AG00J7EJ(AGN-PC-0JNB42)
Synonyms:
MDL No:
Molecular Formula: C4H6N2OS
Molecular Weight: 130.1682

Identification/Properties


Computed Properties
Molecular Weight:
130.165g/mol
XLogP3:
0.1
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
2
Rotatable Bond Count:
0
Exact Mass:
130.02g/mol
Monoisotopic Mass:
130.02g/mol
Topological Polar Surface Area:
80.8A^2
Heavy Atom Count:
8
Formal Charge:
0
Complexity:
154
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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NMR Spectrum


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Chemical Structure



2-Amino-5-methylthiazol-4(5H)-one, also known as AMT, is a versatile compound widely used in chemical synthesis. This compound serves as a key building block for the synthesis of various intermediates and pharmaceuticals. Due to its unique structure and reactivity, AMT is commonly employed in the production of thiazole derivatives, which have diverse applications in the pharmaceutical industry.In chemical synthesis, 2-Amino-5-methylthiazol-4(5H)-one acts as a nucleophilic reactant and participates in a range of reactions including condensation, substitution, and cyclization processes. Its amino and thiazole functional groups enable it to undergo selective reactions with different electrophiles, facilitating the formation of complex molecules with specific biological activities.AMT is particularly valued for its role in the synthesis of thiazole-containing compounds, which exhibit a wide spectrum of biological properties such as antimicrobial, antitumor, and anti-inflammatory activities. By incorporating AMT into organic synthesis routes, chemists can access a variety of functionalized thiazole derivatives that serve as important scaffolds in drug discovery and development.Moreover, the ability of 2-Amino-5-methylthiazol-4(5H)-one to engage in diverse synthetic transformations makes it a valuable tool for accessing structurally complex molecules with enhanced biological activity and potential therapeutic benefits. Its versatility and utility in chemical synthesis make AMT a valuable asset in the toolkit of organic chemists aiming to design and create novel molecules for various applications in medicinal chemistry and materials science.