2,5-Pyrrolidinedione, 1-[(4-benzoylbenzoyl)oxy]-


Chemical Name: 2,5-Pyrrolidinedione, 1-[(4-benzoylbenzoyl)oxy]-
CAS Number: 91990-88-4
Product Number: AG00GV97(AGN-PC-0KKOY5)
Synonyms:
MDL No:
Molecular Formula: C18H13NO5
Molecular Weight: 323.2995

Identification/Properties


Computed Properties
Molecular Weight:
323.304g/mol
XLogP3:
2.2
Hydrogen Bond Donor Count:
0
Hydrogen Bond Acceptor Count:
5
Rotatable Bond Count:
5
Exact Mass:
323.079g/mol
Monoisotopic Mass:
323.079g/mol
Topological Polar Surface Area:
80.8A^2
Heavy Atom Count:
24
Formal Charge:
0
Complexity:
514
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information


GHS Pictogram:
Signal Word:
Danger
UN#:
3077
Hazard Statements:
H400
Precautionary Statements:
P273
Class:
9
Packing Group:

NMR Spectrum


Other Analytical Data


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Chemical Structure



4-(N-Succinimidylcarboxy)benzophenone is a versatile compound widely utilized in chemical synthesis as a key crosslinking reagent. Its primary application lies in the functionalization of biomolecules, particularly proteins and peptides, for various research and industrial purposes. This compound acts as a coupling agent, forming stable amide bonds between the amino groups of proteins and peptides, enabling the conjugation of different molecules or tags.In peptide chemistry, 4-(N-Succinimidylcarboxy)benzophenone is commonly employed to facilitate the modification of peptides with fluorophores, biotin, or other functional groups for labeling and tracking studies. Additionally, it is utilized in the synthesis of peptide nucleic acids (PNAs) to enhance their binding affinity and stability.Furthermore, this reagent plays a crucial role in the development of protein-drug conjugates for targeted drug delivery systems. By linking therapeutic molecules to specific sites on proteins, 4-(N-Succinimidylcarboxy)benzophenone enables the selective delivery of drugs to desired locations within the body, minimizing off-target effects and enhancing therapeutic efficacy.Overall, the strategic application of 4-(N-Succinimidylcarboxy)benzophenone in chemical synthesis enables precise modifications of biomolecules, paving the way for advanced research in fields such as bioconjugation, drug delivery, and peptide chemistry.