Boronic acid, (5-methoxy-1H-indol-2-yl)-


Chemical Name: Boronic acid, (5-methoxy-1H-indol-2-yl)-
CAS Number: 282528-61-4
Product Number: AG00BJUC(AGN-PC-0L6YL6)
Synonyms:
MDL No:
Molecular Formula: C9H10BNO3
Molecular Weight: 190.9916

Identification/Properties


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GHS Pictogram:
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UN#:
-
Hazard Statements:
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Class:
-
Packing Group:
-

NMR Spectrum


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Chemical Structure



(5-Methoxy-1H-indol-2-yl)boronic acid is a versatile compound widely utilized in chemical synthesis, particularly in the field of organic chemistry. Known for its remarkable reactivity and compatibility with various functional groups, this boronic acid derivative serves as a valuable building block in the creation of complex molecules.Commonly employed as a powerful coupling reagent in Suzuki-Miyaura cross-coupling reactions, (5-Methoxy-1H-indol-2-yl)boronic acid plays a crucial role in forming carbon-carbon bonds between aryl or heteroaryl compounds. This reaction, catalyzed by palladium, allows for the efficient assembly of biaryl structures, which are prevalent in the synthesis of pharmaceuticals, agrochemicals, and materials science.Furthermore, the presence of the boronic acid moiety enables (5-Methoxy-1H-indol-2-yl)boronic acid to participate in other important transformations, such as nucleophilic additions, Suzuki-Heck reactions, and directed metalation processes. By judiciously incorporating this compound into synthetic pathways, chemists can access a wide array of diversely functionalized indole derivatives, with potential applications in drug discovery and medicinal chemistry.Overall, the strategic utilization of (5-Methoxy-1H-indol-2-yl)boronic acid in chemical synthesis exemplifies its significance as a key reagent for constructing intricate molecular architectures with precision and efficiency.