Boronic acid, (2,4,6-trimethoxyphenyl)-


Chemical Name: Boronic acid, (2,4,6-trimethoxyphenyl)-
CAS Number: 135159-25-0
Product Number: AG003FNK(AGN-PC-0L71XX)
Synonyms:
MDL No:
Molecular Formula: C9H13BO5
Molecular Weight: 212.0075

Identification/Properties


Properties
MP:
96-100℃
BP:
413.8°C at 760 mmHg
Storage:
Inert atmosphere;-10 ℃;
Form:
Solid
Computed Properties
Molecular Weight:
212.008g/mol
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
5
Rotatable Bond Count:
4
Exact Mass:
212.086g/mol
Monoisotopic Mass:
212.086g/mol
Topological Polar Surface Area:
68.2A^2
Heavy Atom Count:
15
Formal Charge:
0
Complexity:
175
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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NMR Spectrum


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Chemical Structure



2,4,6-Trimethoxyphenylboronic acid is a versatile organic compound widely used in chemical synthesis as a key building block in the preparation of various functionalized molecules. Its unique structure and properties make it an indispensable reagent in the field of organic chemistry.In chemical synthesis, 2,4,6-Trimethoxyphenylboronic acid serves as a valuable precursor for the construction of biaryl compounds through Suzuki-Miyaura cross-coupling reactions. This reaction involves the coupling of an arylboronic acid with an aryl halide or pseudohalide in the presence of a palladium catalyst, leading to the formation of a new carbon-carbon bond. This methodology is extensively employed in the synthesis of complex organic molecules, pharmaceuticals, agrochemicals, and materials.Furthermore, 2,4,6-Trimethoxyphenylboronic acid plays a crucial role in the synthesis of various natural products, pharmaceutical intermediates, and functional materials. Its ability to undergo selective functionalization reactions, such as halogenation, arylation, and alkylation, makes it a valuable tool for the modification of organic molecules with specific desired properties.Overall, the application of 2,4,6-Trimethoxyphenylboronic acid in chemical synthesis enables chemists to access a wide range of structurally diverse and complex compounds, driving innovation and advancement in the field of organic chemistry.