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Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

Silane, trimethyl[[(4-methylphenyl)sulfonyl]ethynyl]-

Cc1ccc(cc1)S(=O)(=O)C#C[Si](C)(C)C Request for Quotation
Chemical Name: Silane, trimethyl[[(4-methylphenyl)sulfonyl]ethynyl]-
CAS Number: 34452-56-7
Product Number: AG003U1A(AGN-PC-0LM7HA)
Synonyms:
MDL No:
Molecular Formula: C12H16O2SSi
Molecular Weight: 252.40474

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Chemical Structure


p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone is a versatile compound widely used in chemical synthesis, especially in organic chemistry. Its unique structure and reactivity make it a valuable building block for the construction of various organic molecules.One key application of p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone is as a reagent in Sonogashira cross-coupling reactions. In this reaction, the ethynyl group of the sulfone serves as an excellent electrophile, allowing for the formation of new carbon-carbon bonds with aryl or vinyl halides in the presence of a palladium catalyst. This reaction is highly valuable for the synthesis of complex organic molecules, such as pharmaceutical compounds and natural products.Furthermore, the trimethylsilyl group attached to the ethynyl moiety provides steric hindrance and stability to the intermediate species, allowing for selective and controlled cross-coupling reactions. This feature makes p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone a preferred reagent in the synthesis of functionalized alkynes.Overall, the application of p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone in chemical synthesis offers chemists a powerful tool for the efficient construction of diverse organic compounds with high yields and selectivity.