2-bromo-4,5-dimethyl-1,3-thiazole


Chemical Name: 2-bromo-4,5-dimethyl-1,3-thiazole
CAS Number: 29947-24-8
Product Number: AG00383I(AGN-PC-0MW245)
Synonyms:
MDL No:
Molecular Formula: C5H6BrNS
Molecular Weight: 192.0768

Identification/Properties


Computed Properties
Molecular Weight:
192.074g/mol
XLogP3:
2.8
Hydrogen Bond Donor Count:
0
Hydrogen Bond Acceptor Count:
2
Rotatable Bond Count:
0
Exact Mass:
190.94g/mol
Monoisotopic Mass:
190.94g/mol
Topological Polar Surface Area:
41.1A^2
Heavy Atom Count:
8
Formal Charge:
0
Complexity:
88.5
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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NMR Spectrum


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Chemical Structure



2-Bromo-4,5-dimethylthiazole is a versatile compound commonly used in chemical synthesis as a key building block for various organic reactions. Its unique structure and reactivity make it a valuable tool in the creation of pharmaceuticals, agrochemicals, and materials.In organic synthesis, 2-Bromo-4,5-dimethylthiazole serves as a useful starting material for the preparation of thiazole-containing compounds. It can undergo various substitution, coupling, and cyclization reactions to introduce different functional groups or create complex molecular structures. Its bromine atom provides a handle for further functionalization, enabling the synthesis of diverse derivatives with tailored properties.One of the significant applications of 2-Bromo-4,5-dimethylthiazole is in the pharmaceutical industry, where it is employed in the development of new drugs and bioactive compounds. Thiazole derivatives are known for their pharmacological activities, including antimicrobial, antifungal, and anticancer properties. By incorporating 2-Bromo-4,5-dimethylthiazole into drug molecules, chemists can modulate the biological effects and enhance the therapeutic potential of the final product.Furthermore, 2-Bromo-4,5-dimethylthiazole plays a crucial role in agrochemical synthesis by serving as a precursor for designing novel pesticides, herbicides, and fungicides. The thiazole ring system is often found in active ingredients of agrochemicals due to its efficacy in targeting specific biological pathways in pests or weeds. By utilizing 2-Bromo-4,5-dimethylthiazole as a starting point, chemists can develop sustainable and effective crop protection solutions.Overall, the versatility and synthetic utility of 2-Bromo-4,5-dimethylthiazole make it a valuable asset in chemical synthesis, enabling the creation of diverse organic compounds with applications in pharmaceuticals, agrochemicals, and materials science.