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Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

Benzoic acid, 2-[[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]methyl]-

O=C(OCC1c2ccccc2c2c1cccc2)NCc1ccccc1C(=O)O Request for Quotation
Chemical Name: Benzoic acid, 2-[[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]methyl]-
CAS Number: 219640-94-5
Product Number: AG007OQJ(AGN-PC-0N9BI7)
Synonyms:
MDL No:
Molecular Formula: C23H19NO4
Molecular Weight: 373.4013

Identification/Properties

Computed Properties
Molecular Weight:
373.408g/mol
XLogP3:
4.1
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
4
Rotatable Bond Count:
6
Exact Mass:
373.131g/mol
Monoisotopic Mass:
373.131g/mol
Topological Polar Surface Area:
75.6A^2
Heavy Atom Count:
28
Formal Charge:
0
Complexity:
543
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

GHS Pictogram:
Signal Word:
Warning
UN#:
N/A
Hazard Statements:
H302-H315-H319-H335
Precautionary Statements:
P261-P305+P351+P338
Class:
N/A
Packing Group:
N/A

NMR Spectrum

Other Analytical Data

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Chemical Structure


Fmoc-(2-aminomethyl) benzoic acid is a versatile building block commonly used in chemical synthesis, particularly in the field of peptide synthesis. As a coupling agent, it plays a crucial role in creating peptide bonds by reacting with amino acids to form peptide chains. The Fmoc (fluorenylmethyloxycarbonyl) protecting group ensures selective reactivity at the amino group while providing stability to the molecule during synthesis.Additionally, Fmoc-(2-aminomethyl) benzoic acid facilitates solid-phase peptide synthesis by efficiently anchoring the growing peptide chain to a solid support, allowing for stepwise elongation of the sequence. Its compatibility with standard amino acid coupling protocols makes it an essential component in the production of complex peptides with high purity and yield.Moreover, the presence of the 2-aminomethyl functionality enhances the solubility and stability of the peptide during synthesis, reducing aggregation and increasing overall efficiency. This feature makes Fmoc-(2-aminomethyl) benzoic acid particularly valuable in the construction of difficult peptide sequences or for peptides prone to aggregation.In conclusion, Fmoc-(2-aminomethyl) benzoic acid is a vital tool in peptide chemistry, contributing to the synthesis of diverse peptides with specific biological activities or structural properties. Its strategic application in chemical synthesis enables the efficient production of peptides for various research and industrial applications.