Spiro[cyclopropane-1,3'-[3H]indol]-2'(1'H)-one


Chemical Name: Spiro[cyclopropane-1,3'-[3H]indol]-2'(1'H)-one
CAS Number: 13861-75-1
Product Number: AG0018V3(AGN-PC-0NJYC2)
Synonyms:
MDL No:
Molecular Formula: C10H9NO
Molecular Weight: 159.1846

Identification/Properties


Computed Properties
Molecular Weight:
159.188g/mol
XLogP3:
1.1
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
1
Rotatable Bond Count:
0
Exact Mass:
159.068g/mol
Monoisotopic Mass:
159.068g/mol
Topological Polar Surface Area:
29.1A^2
Heavy Atom Count:
12
Formal Charge:
0
Complexity:
232
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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Chemical Structure



The unique molecular structure of Spiro[cyclopropane-1,3'-indolin]-2'-one makes it a versatile and valuable tool in modern chemical synthesis. This compound serves as a valuable building block in the creation of complex organic molecules due to its ability to participate in various synthetic transformations.Spiro[cyclopropane-1,3'-indolin]-2'-one is particularly useful in the construction of spirocyclic frameworks, which are prevalent in natural products and bioactive compounds. Its rigid spirocyclic structure imparts significant stereochemical control, enabling chemists to generate diverse and highly functionalized compounds with high selectivity. Moreover, the strained cyclopropane ring in Spiro[cyclopropane-1,3'-indolin]-2'-one can undergo unique ring-opening reactions, leading to the formation of intricate molecular architectures not easily accessible through conventional synthetic routes.In addition to its utility in the synthesis of complex molecules, Spiro[cyclopropane-1,3'-indolin]-2'-one has demonstrated promising applications in medicinal chemistry, where spirocyclic motifs are often associated with enhanced biological activities. By incorporating this scaffold into drug-like molecules, researchers can explore new chemical space and potentially develop novel therapeutics with improved pharmacological properties.Overall, the strategic incorporation of Spiro[cyclopropane-1,3'-indolin]-2'-one in chemical synthesis enables rapid access to structurally diverse compounds with potential applications in drug discovery, materials science, and other areas of molecular research.