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Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

1-Piperidinecarboxylic acid, 2-(hydroxymethyl)-, 1,1-dimethylethyl ester,(2S)-

OC[C@@H]1CCCCN1C(=O)OC(C)(C)C Request for Quotation
Chemical Name: 1-Piperidinecarboxylic acid, 2-(hydroxymethyl)-, 1,1-dimethylethyl ester,(2S)-
CAS Number: 134441-93-3
Product Number: AG003CNY(AGN-PC-0PK9OY)
Synonyms:
MDL No: MFCD04973121
Molecular Formula: C11H21NO3
Molecular Weight: 215.2893

Identification/Properties

Properties
MP:
73-75℃
BP:
308°C at 760 mmHg
Storage:
Keep in dry area;2-8℃;
Form:
Solid
Computed Properties
Molecular Weight:
215.293g/mol
XLogP3:
1.3
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
3
Rotatable Bond Count:
3
Exact Mass:
215.152g/mol
Monoisotopic Mass:
215.152g/mol
Topological Polar Surface Area:
49.8A^2
Heavy Atom Count:
15
Formal Charge:
0
Complexity:
222
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
1
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

GHS Pictogram:
Signal Word:
Warning
UN#:
N/A
Hazard Statements:
H302-H315-H319-H335
Precautionary Statements:
P261-P305+P351+P338
Class:
N/A
Packing Group:
N/A

NMR Spectrum

Other Analytical Data

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Chemical Structure


(S)-1-Boc-2-(Hydroxymethyl)piperidine is a versatile compound widely used in chemical synthesis as a chiral building block. Its unique structure, featuring a Boc (tert-butoxycarbonyl) group and a hydroxymethyl moiety attached to a piperidine ring, lends itself well to a variety of reactions and transformations in organic synthesis. One of the key applications of (S)-1-Boc-2-(Hydroxymethyl)piperidine is in asymmetric synthesis, where it serves as a valuable starting material for the preparation of enantiomerically pure compounds. The chiral nature of the molecule allows for the selective formation of single enantiomers, which is crucial in the synthesis of pharmaceuticals, agrochemicals, and other bioactive molecules where chirality plays a significant role in biological activity.Additionally, the hydroxymethyl group in (S)-1-Boc-2-(Hydroxymethyl)piperidine can undergo various functional group transformations, such as oxidation, reduction, or substitution reactions, enabling the synthesis of diverse chemical entities. The Boc protecting group provides stability to the piperidine nitrogen atom and can be selectively removed under mild conditions to reveal the free amine functionality for further derivatization.Overall, the strategic incorporation of (S)-1-Boc-2-(Hydroxymethyl)piperidine in chemical synthesis allows for the construction of complex molecules with high stereochemical control, making it a valuable tool for organic chemists working in the field of asymmetric synthesis and drug discovery.