Pentanedioic acid, 3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-,mono(1,1-dimethylethyl) ester, (3R)-


Chemical Name: Pentanedioic acid, 3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-,mono(1,1-dimethylethyl) ester, (3R)-
CAS Number: 209252-17-5
Product Number: AG002K4R(AGN-PC-0QWRSK)
Synonyms:
MDL No:
Molecular Formula: C24H26NO6-
Molecular Weight: 424.4663

Identification/Properties


Properties
Storage:
2-8℃;
Form:
Solid
Computed Properties
Molecular Weight:
425.481g/mol
XLogP3:
3.4
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
6
Rotatable Bond Count:
10
Exact Mass:
425.184g/mol
Monoisotopic Mass:
425.184g/mol
Topological Polar Surface Area:
102A^2
Heavy Atom Count:
31
Formal Charge:
0
Complexity:
635
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
1
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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NMR Spectrum


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Chemical Structure



Fmoc-β-HoAsp(OtBu)-OH, also known as Fluorenylmethyloxycarbonyl beta-hydroxyaspartic acid (tert-butyl ester), is a valuable reagent commonly used in chemical synthesis processes. This compound plays a crucial role in solid-phase peptide synthesis as a protecting group strategy for sensitive hydroxyaspartic acid residues. By utilizing Fmoc-β-HoAsp(OtBu)-OH, chemists can safeguard the hydroxyaspartic acid moiety during peptide assembly and manipulation, while enabling selective deprotection when required. This versatile reagent facilitates the efficient and controlled construction of complex peptide structures, making it an indispensable tool in the realm of peptide and protein chemistry.