Chemical Name: | Palladium, [1,1'-bis[bis(1-methylethyl)phosphino-kP]ferrocene]dichloro-,(SP-4-2)- |
CAS Number: | 215788-65-1 |
Product Number: | AG0039UX(AGN-PC-0QY50V) |
Synonyms: | |
MDL No: | |
Molecular Formula: | C22H28Cl2FeP2Pd |
Molecular Weight: | 587.5762 |
The (1,1'-Bis(diisopropylphosphino)ferrocene)dichloropalladium (Pd(dppf)Cl2) complex is a versatile and effective catalyst widely used in chemical synthesis. This complex plays a crucial role in various cross-coupling reactions, particularly in the Suzuki-Miyaura and Heck reactions. These reactions are essential in the construction of carbon-carbon and carbon-heteroatom bonds, allowing for the efficient synthesis of complex organic molecules.Pd(dppf)Cl2 acts as a catalyst by facilitating the oxidative addition of aryl halides or vinyl halides to palladium, forming reactive Pd(II) intermediates that can undergo transmetallation with organoboron or organotin reagents. Subsequent reductive elimination leads to the formation of the desired cross-coupled product. The presence of the dppf ligand in the complex enhances its stability and reactivity, making it particularly effective in challenging reactions that require high catalytic activity.In addition to its application in cross-coupling reactions, Pd(dppf)Cl2 is also employed in other transformations such as carbon-hydrogen activation, carbonylation, and cyclopropanation reactions. Its unique structure and reactivity make it a valuable tool for synthetic chemists seeking to streamline the preparation of complex organic compounds with high efficiency and selectivity.