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Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

b-D-Glucopyranosiduronic acid,5-[(2E)-5-carboxy-3-methyl-2-pentenyl]-1,3-dihydro-6-methoxy-7-methyl-3-oxo-4-isobenzofuranyl

COc1c(C/C=C(/CCC(=O)O)C)c(O[C@@H]2OC(C(=O)O)[C@H](C([C@@H]2O)O)O)c2c(c1C)COC2=O Request for Quotation
Chemical Name: b-D-Glucopyranosiduronic acid,5-[(2E)-5-carboxy-3-methyl-2-pentenyl]-1,3-dihydro-6-methoxy-7-methyl-3-oxo-4-isobenzofuranyl
CAS Number: 31528-44-6
Product Number: AG007J03(AGN-PC-0R6VU3)
Synonyms:
MDL No:
Molecular Formula: C23H28O12
Molecular Weight: 496.4612

Identification/Properties

Computed Properties
Molecular Weight:
496.465g/mol
XLogP3:
1.1
Hydrogen Bond Donor Count:
5
Hydrogen Bond Acceptor Count:
12
Rotatable Bond Count:
9
Exact Mass:
496.158g/mol
Monoisotopic Mass:
496.158g/mol
Topological Polar Surface Area:
189A^2
Heavy Atom Count:
35
Formal Charge:
0
Complexity:
827
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
5
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

NMR Spectrum

Other Analytical Data

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Chemical Structure


Mycophenolic acid β-D-glucuronide, also known as MPA-G, serves as a valuable reagent in chemical synthesis due to its ability to inhibit inosine monophosphate dehydrogenase (IMPDH). This crucial enzyme is involved in the biosynthesis of guanine nucleotides, making MPA-G a potent tool for disrupting nucleotide metabolism pathways.In the realm of chemical synthesis, MPA-G is commonly utilized as a prodrug of mycophenolic acid (MPA). Through enzymatic cleavage by β-glucuronidase present in biological systems, MPA-G can release MPA, which is a well-known immunosuppressant and anticancer agent. This controlled release mechanism not only enhances the specificity of drug targeting but also offers a means to regulate the pharmacokinetics of MPA in various applications.The use of Mycophenolic acid β-D-glucuronide in chemical synthesis holds promise for creating innovative drug delivery systems, developing prodrugs with improved bioavailability, and exploring novel therapeutic strategies. Its compatibility with biocompatible conditions and ability to modulate drug release kinetics make it a versatile tool for advancing pharmaceutical research and development.