Boc-Tyr-OH


Chemical Name: Boc-Tyr-OH
CAS Number: 3978-80-1
Product Number: AG003A7C(AGN-PC-0WACO4)
Synonyms:
MDL No:
Molecular Formula: C14H19NO5
Molecular Weight: 281.3044

Identification/Properties


Computed Properties
Molecular Weight:
281.308g/mol
XLogP3:
1.5
Hydrogen Bond Donor Count:
3
Hydrogen Bond Acceptor Count:
5
Rotatable Bond Count:
6
Exact Mass:
281.126g/mol
Monoisotopic Mass:
281.126g/mol
Topological Polar Surface Area:
95.9A^2
Heavy Atom Count:
20
Formal Charge:
0
Complexity:
342
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
1
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information


GHS Pictogram:
Signal Word:
Warning
UN#:
N/A
Hazard Statements:
H302-H315-H319-H332-H335
Precautionary Statements:
P261-P280-P305+P351+P338
Class:
N/A
Packing Group:
N/A

NMR Spectrum


Other Analytical Data


Request for Quotation


Customer Feedback


Chemical Structure



N-(tert-Butyloxycarbonyl)-L-tyrosine, also known as Boc-L-tyrosine, is a commonly used compound in chemical synthesis, particularly in the field of peptide synthesis. This compound serves as a versatile amino acid derivative that plays a crucial role in the protection and derivatization of the tyrosine amino acid residue.In peptide synthesis, Boc-L-tyrosine is often utilized as a protected building block due to its ability to selectively mask the amino group of tyrosine. By introducing this Boc protecting group, the reactivity of the amino group is decreased, preventing unwanted side reactions during peptide chain elongation. This protection strategy allows for the sequential assembly of peptides with precision and efficiency.Moreover, Boc-L-tyrosine can be incorporated into peptide sequences with other protected amino acids using solid-phase peptide synthesis or solution-phase peptide synthesis methods. The Boc group can be selectively removed under mild conditions such as treatment with acids like trifluoroacetic acid (TFA), releasing the free amino group for further coupling reactions.Overall, N-(tert-Butyloxycarbonyl)-L-tyrosine is a valuable tool in chemical synthesis, offering a strategic approach to peptide assembly and modification, making it an indispensable component in the field of organic chemistry and biochemistry.