1-Chloro-8-(trifluoromethyl)isoquinoline


Chemical Name: 1-Chloro-8-(trifluoromethyl)isoquinoline
CAS Number: 1196152-92-7
Product Number: AG000PBB(AGN-PC-0WAH6R)
Synonyms:
MDL No:
Molecular Formula: C10H5ClF3N
Molecular Weight: 231.6016

Identification/Properties


Safety Information


GHS Pictogram:
N/A
Signal Word:
UN#:
-
Hazard Statements:
-
Precautionary Statements:
Class:
-
Packing Group:
-

NMR Spectrum


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Chemical Structure



1-Chloro-6-(trifluoromethyl)isoquinoline is a versatile compound widely utilized in chemical synthesis as a key building block for the preparation of various pharmaceuticals, agrochemicals, and advanced materials. Its unique structure, characterized by the presence of a trifluoromethyl group attached to an isoquinoline ring, imparts distinctive properties that make it valuable in organic synthesis.In research and development, 1-Chloro-6-(trifluoromethyl)isoquinoline serves as a valuable intermediate for the construction of complex molecules through diverse reactions such as nucleophilic substitution, cross-coupling, and cycloaddition processes. Its trifluoromethyl group enhances the compound's lipophilicity and bioavailability, making it an attractive candidate for drug discovery programs.Moreover, the isoquinoline moiety in this compound offers a plethora of opportunities for further functionalization, enabling the synthesis of novel compounds with tailored properties. By leveraging the reactivity of the chlorine and trifluoromethyl substituents, chemists can access a wide range of structural motifs that are inaccessible with other starting materials.Overall, 1-Chloro-6-(trifluoromethyl)isoquinoline plays a crucial role in advancing the field of chemical synthesis by enabling the efficient and strategic construction of diverse molecular architectures with potential applications in medicine, agriculture, and materials science.