1. Home
  2. (R)-2-(2,5-difluorophenyl)pyrrolidine, >97%ee (HCL salt form)

Contact Angene

Tel: +852 8191 6999

Email: sales@angenechemical.com

Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

(R)-2-(2,5-difluorophenyl)pyrrolidine, >97%ee (HCL salt form)

Fc1ccc(c(c1)[C@H]1CCCN1)F.Fc1ccc(c(c1)[C@H]1CCCN1)F.Cl.Cl Request for Quotation
Chemical Name: (R)-2-(2,5-difluorophenyl)pyrrolidine, >97%ee (HCL salt form)
CAS Number: 1218935-60-4
Product Number: AG0016C1(AGN-PC-0WALXR)
Synonyms:
MDL No:
Molecular Formula: C20H24Cl2F4N2
Molecular Weight: 439.3176

Identification/Properties

Computed Properties
Molecular Weight:
219.66g/mol
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
3
Rotatable Bond Count:
1
Exact Mass:
219.063g/mol
Monoisotopic Mass:
219.063g/mol
Topological Polar Surface Area:
12A^2
Heavy Atom Count:
14
Formal Charge:
0
Complexity:
174
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
1
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
2
Compound Is Canonicalized:
Yes

Safety Information

GHS Pictogram:
Signal Word:
Warning
UN#:
N/A
Hazard Statements:
H302-H315-H319-H335
Precautionary Statements:
P261-P305+P351+P338
Class:
N/A
Packing Group:
N/A

NMR Spectrum

Other Analytical Data

Request for Quotation

Customer Feedback

Chemical Structure


The (R)-2-(2,5-Difluorophenyl)pyrrolidine hydrochloride is a versatile compound widely utilized in chemical synthesis as a chiral building block. Its asymmetric structure and unique reactivity make it a valuable tool for constructing complex molecules with high stereoselectivity. In particular, this compound is frequently employed in the synthesis of pharmaceutical intermediates and agrochemicals where chirality plays a crucial role in determining biological activity. Its application in asymmetric catalysis and asymmetric synthesis has been instrumental in the development of novel drug candidates and bioactive compounds. By incorporating (R)-2-(2,5-Difluorophenyl)pyrrolidine hydrochloride into synthetic routes, chemists can effectively control the stereochemistry of their target molecules, paving the way for the creation of new therapeutics and functional materials.